If you think you're well geared, think again. Det0x parades his monstrously equipped Weapon Throw barb as he takes down MP 10 Azmodan in under a minute.
Armed with Echoing Fury, The Three Hundredth Spear and all the perfect rubies in the world, Det0x evaporates the 138M hit points Azmodan in a little more than 50 seconds, giving him approximately 2,662,000 DPS. His items and skill build: here.